PUBLICATIONS
Toker, D., McCrimmon, CM., Cao, Q., Pandey, A., Guzman, A., Shriram, A., Hudson, A., Monti, MM., Samarasinghe, RA. Human Brain Assembloids Model Anesthetic-Induced Neural Dynamics. British Journal of Anaesthesia. Accepted July 2026.
Guzman, AR., McCrimmon, CM., Toker, D., Novitch, BG., Watanabe, M., Samarasinghe, RA. Protocol for Characterization of Spatiotemporal Network Dynamics in Cortical and Hippocampal Assembloids. STAR Protoc. Epub 2026 Mar 27;7(2):104463. PMID: 41904955.
McCrimmon, CM., Toker, D., Pahos, M., Lozano, K., Lin, JJ., Parent, J., Tidball, A., Zheng, J., Molnar, L., Mody, I., Novitch, BG., Samarasinghe, RA. Modeling cortical versus hippocampal network dysfunction in a human brain assembloid model of epilepsy and intellectual disability. Cell Rep. Epub 2025 Sep 23;44(9):116217.
Atamian, A., Birtele, M., Hosseini, N., Nguyen, T., Seth, A., Del Dosso, A., Paul, S., Tedeschi, N., Taylor, R., Coba, MP., Samarasinghe, RA., Lois, C., and Quadratto, G. Human cerebellar organoids with functional Purkinje cells. Cell Stem Cell. 2024 Jan 04;31(1):39-51. PMID: 38181749.
Samarasinghe, RA., Kanuparthi, P., DeFranco, D., Di Maio, R. Transient Muscarinic and Glutamatergic Stimulation of Neural Stem Cells Trigger Acute and Persistent Changes in Differentiation. Neurobiol of Dis. 2014 Oct 70:252-61. PMCID: PMC4152385.
Samarasinghe. RA., Witchel, S., DeFranco, D. Cooperativity and Complementarity: Synergies in Non-Classical and Classical Glucocorticoid Signaling. Cell Cycle. 2012 Aug 1 (15):2819-27 PMCID: PMC3419059.
Samarasinghe, RA., Di Maio R., Volonte, D., Galbiati F., Lewis, M., Romero, G., DeFranco, D. Non-genomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation. Proc Natl Acad Sci USA. 2011 Sep 19. PMCID: PMC3189065.
Bales JW, Yan HQ, Ma X, Li Y, Samarasinghe RA., Dixon CE. The dopamine and cAMP regulated phosphoprotein, 32 kDa (DARPP-32) signaling pathway: a novel therapeutic target in traumatic brain injury. Exp Neurol. 201. Epub 2011 Mar 1. PMCID: PMC3110667.
Samarasinghe RA. The urgent need to increase support for the NIH’s MD-PhD student fellowships. Acad Med. 2011 Mar;86(3):277; PubMed PMID: 21346431.
Ho, Y*, Samarasinghe, RA.*, Knoch ME., Lewis M, Aizenman E, DeFranco DB. Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death. Mol Pharmacol. 2008 Oct; 74(4):1141-51. PMCID: PMC2575064.
*Both authors contributed equally to this work and should be considered co-first authors
Samarasinghe, RA., Tailor, P., Tamura, T., Kaisho, T., Akira S., Ozato, K. Induction of an Anti-Inflammatory Cytokine, IL-10, in Dendritic Cells After Toll-like Receptor Signaling.
Journal of Interferon and Cytokine Research. 2006; 26: 893-900. PMID:17238832